Bosses in Biomutant refer to special Enemies that are a distinctly more powerful than their regular counterparts. Bosses are often larger, tougher and possess special abilities that present a much bigger challenge to overcome. Defeating some bosses are required in order to progress the story and main campaign, while others are optional challenges for the daring. There are also a handful of World Eaters, which are colossal Boss-type enemies that feast on the roots of the Tree of Life and are directly tied to the main story. This page lists all Bosses found in the game as well as relevant information on how to defeat them, loot drops and more.
Biomutant Bosses Guide

Lupa-Lupin
The past coming to haunt the present.

Emissive Whisper
Netra Fortress Final Boss

Sniper
Antaki Fortress Final Boss

Slimy Kong
Lotus Fortress Final Boss

Fluoron Dew
Pichu Fortress Final Boss

Common Contagon
Jagni Fortress Final Boss
World Eaters

Jumbo Puff
The Western Worldeater

Porky Puff
The Southeastern Worldeater

Hoof Puff
The Northeastern Worldeater

Murk Puff
The Northwestern Worldeater